Pharma Industrial India Magazine - July - August 2024

Waters Corporation introduces the TA Instruments Rapid Screening-Differential Scanning Calorimeter (TA Instruments RS-DSC), designed for biopharmaceuti- cal developers. The TA Instruments RS-DSC is a high-throughput DSC for precise thermal stability testing of high-concentration bi- ologic formulations specifically for anti - body drugs and engineered proteins. The TA Instruments Rapid Screen- ing-Differential Scanning Calorimeter revolutionizes thermal stability testing of biological drugs, helping biopharma- ceutical labs streamline analysis, and accelerate time to market. Demand is increasing for higher concen- tration injectable drugs, and biologic de- velopers are looking for stability testing that is fast and efficient. Water’s new Rapid Screening-DSC meets these needs by providing a high-throughput alternative to existing capillary DSCs and a more reliable and accurate option to differential scanning fluorescence (DSF) technologies. The TA Instruments RS-DSC offers a more convenient and accurate solu- tion to assess biological drug stability and quality by employing disposable, low-sample volume microfluidic chips (MFCs) that enable up to 24 simulta - neous measurements. This reduces or eliminates the need for sample dilution, and repetitive instrument cleaning, and lowers contamination risk. Its unique design avoids the sensitivity challenges of DSF methods, enabling it to produce more accurate data on high-concentra- tion samples. Additionally, the TA Instruments RS-DSC features state-of-the-art automated soft- ware that provides rapid, effortless, pre- cise, and in-depth insights about a sam- ple’s thermodynamic properties. The TA Instruments RS-DSC is now avail- able globally to all customers through the TA Instruments Division of Waters Corporation. Waters’ TA Instruments RS-DSC Offers Fast Thermal Stability Testing for Antibody Drugs PRODUCT PHARMA INDUSTRIALINDIA · JUL-AUG 24 25