News about Clinical Trials

Phrontline Biopharma Announces First Patient Dosed in Phase-I Clinical Trial of TJ101

The Phase 1 study of TJ101 will assess its safety, tolerability, pharmacokinetics, and early anti-tumor activity in various solid tumors, using a dose escalation and expansion cohort design.

Clinical Trials | 15/09/2025 | By Dineshwori |  110

NMPA Clears Zhimeng Biopharma's Drug for Phase-II Epilepsy Trial

Zhimeng Biopharma’s drug for Phase II epilepsy trial will be evaluated in a randomized, double-blind, placebo-controlled multinational study to test its efficacy, safety, and tolerability as an adjunct therapy in adults with focal epilepsy.

Clinical Trials | 13/09/2025 | By Dineshwori |  174

Modular Medical Completes MODD1 Clinical Study, Advances Toward Next-Gen Pivot Pump Launch

US-based insulin delivery technology company Modular Medical has announced the successful completion of a clinical study with its MODD1 pump.

Clinical Trials | 12/09/2025 | By Dineshwori |  263

Sanofi Drug Earns Fast Track Status for Wet AMD in US

Sanofi is evaluating SAR402663 in a Phase 1/2 trial (NCT06660667) for neovascular AMD. The gene therapy targets abnormal blood vessel growth, reduces retinal damage, and aims to eliminate the need for frequent intravitreal injections.

Clinical Trials | 11/09/2025 | By Dineshwori |  164

Lilly Drug Jaypirca Delivers Positive Results in CLL Patients

Lilly’s Jaypirca showed a strong Progression-Free Survival (PFS) benefit in front-line CLL, with data from BRUIN studies set to support global label expansion filings.

Clinical Trials | 10/09/2025 | By Dineshwori |  150

Amgen and Kyowa Kirin Report Phase-III Results for Rocatinlimab in Atopic Dermatitis

Amgen and Kyowa Kirin report top-line results from ongoing ASCEND study evaluating Rocatinlimab’s long-term safety and efficacy in adults with moderate to severe Atopic Dermatitis following prior ROCKET trials.

Clinical Trials | 09/09/2025 | By Dineshwori |  214

Mankind Pharma Gets CDSCO Nod to Begin Phase 1 Trials of Novel Autoimmune Drug Candidate MKP11093

Mankind Pharma Ltd., India’s 4th largest pharmaceutical company, today announced that it has received approval from the Central Drugs Standard Control Organisation (CDSCO) to initiate a Phase 1 clinical trial of MKP11093, a novel, orally administered Janus kinase-1 (JAK-1) inhibitor.

Clinical Trials | 08/09/2025 | By Darshana |  160

Medtronic Hugo Robotic System Shows Success in Hernia Repair

Medtronic’s Enable Hernia Repair study marks the first IDE clinical trial in the US for robotic-assisted hernia surgery, evaluating the Hugo RAS system in inguinal and ventral procedures.

Clinical Trials | 06/09/2025 | By Dineshwori |  239

Senhwa Biosciences Secures US FDA Nod to Advance Pidnarulex Trial for MYC-Driven B-Cell Lymphoma

Senhwa Biosciences has received FDA clearance to begin a Phase 1b/2 trial of its novel MYC-targeting drug candidate Pidnarulex (CX-5461) in patients with B-cell lymphoma, marking a potential breakthrough in precision oncology.

Clinical Trials | 06/09/2025 | By Mrinmoy Dey |  207

BioNTech and Duality Biologics reach major breakthrough in breast cancer trial

BioNTech and Duality Biologics have announced a significant advance in cancer drug development with the successful outcome of a Phase III trial for their investigational therapy BNT323, also known as trastuzumab pamirtecan.

Clinical Trials | 06/09/2025 | By Darshana |  211