News about Clinical Trials

Roche's Fenebrutinib Delivers Strong Phase III results as a Potential First-in-Class BTK Inhibitor for Multiple Sclerosis

Roche's Fenebrutinib Delivers Strong Phase III results as a Potential First-in-Class BTK Inhibitor for Multiple Sclerosis

In the pivotal FENtrepid trial, Roche’s BTK inhibitor fenebrutinib demonstrated a meaningful reduction in disability progression in Primary Progressive Multiple Sclerosis (PPMS), performing at least on par with OCREVUS—the current standard and only approved treatment for PPMS.

Clinical Trials | 15/11/2025 | By Dineshwori 284

Sun Pharma Presents Two Posters on Utreglutide at ObesityWeek 2025

Sun Pharma Presents Two Posters on Utreglutide at ObesityWeek 2025

Sun Pharma presented new clinical data on its investigational GLP-1 agonist, Utreglutide, at ObesityWeek 2025, highlighting meaningful reductions in body weight, waist circumference, and lipid parameters across two studies, with the therapy showing a favourable and class-consistent safety profile.

Clinical Trials | 14/11/2025 | By Dineshwori 357

Novartis Reports Promising Results for New Anti-Malaria Drug to Tackle Growing Resistance

Novartis Reports Promising Results for New Anti-Malaria Drug to Tackle Growing Resistance

Novartis’ Phase III trial of KLU156 (GanLum) met its primary endpoint, showing a 97.4 percent PCR-corrected cure rate comparable to Coartem. If approved, GanLum would mark the first major malaria treatment breakthrough in over two decades, targeting drug-resistant parasites.

Clinical Trials | 13/11/2025 | By Dineshwori 204

Daiichi Sankyo Initiates First-in-Human Trial for DS3610, a First-in-Class STING Agonist ADC for Advanced Solid Tumours

Daiichi Sankyo Initiates First-in-Human Trial for DS3610, a First-in-Class STING Agonist ADC for Advanced Solid Tumours

Daiichi Sankyo has dosed the first patient in a phase 1 clinical trial of DS3610, its investigational STING agonist Antibody Drug Conjugate (ADC), marking a key step in advancing novel immunotherapy approaches for patients with advanced solid tumours.

Clinical Trials | 12/11/2025 | By Dineshwori 734

Sun Pharma's Partner Philogen Reports Promising Trends from Phase III Fibromun Trial in Soft Tissue Sarcoma

Sun Pharma's Partner Philogen Reports Promising Trends from Phase III Fibromun Trial in Soft Tissue Sarcoma

Sun Pharmaceutical’s partner Philogen, a Swiss-Italian biotechnology company, has provided an update on the Phase III FIBROSARC trial evaluating Fibromun (L19TNF) in combination with doxorubicin versus doxorubicin alone as first-line treatment for patients with advanced or metastatic Soft Tissue Sarcoma (STS).

Clinical Trials | 12/11/2025 | By Dineshwori 474

OrtoWell Hydraulic Distractor System Proven Safe and Effective in First Multi-Centre Clinical Study

OrtoWell Hydraulic Distractor System Proven Safe and Effective in First Multi-Centre Clinical Study

OrtoWay-US Inc, the US-German MedTech innovator focused on spinal surgery tools for orthopedic vertebral separation, has announced the publication of the first prospective, multi-center clinical study evaluating its OrtoWell Distractor System – the world's first hydraulically powered vertebral distractor.

Clinical Trials | 11/11/2025 | By Dineshwori 212

Sanofi and Regeneron's Dupixent Meets Key Goals in Allergic Fungal Rhinosinusitis; FDA Grants Priority Review

Sanofi and Regeneron's Dupixent Meets Key Goals in Allergic Fungal Rhinosinusitis; FDA Grants Priority Review

Phase 3 results show Dupixent significantly improved nasal symptoms and sinus health in patients aged six and above with allergic fungal rhinosinusitis, supporting its FDA priority review.

Clinical Trials | 10/11/2025 | By Dineshwori 266

Roche's Gazyva/Gazyvaro Shows Positive Results for Systemic Lupus Erythematosus in Phase III trials

Roche's Gazyva/Gazyvaro Shows Positive Results for Systemic Lupus Erythematosus in Phase III trials

The ALLEGORY study met its primary endpoint showing a higher percentage of people achieved a minimum four-point improvement in SLE Responder Index 4 (SRI-4) at one year (52 weeks) with Gazyva/Gazyvaro versus standard therapy.

Clinical Trials | 05/11/2025 | By Dineshwori 304

Johnson & Johnson MedTech Confirms Durability of IVL in Complex Below-the-Knee Lesions in PAD Patients

Johnson & Johnson MedTech Confirms Durability of IVL in Complex Below-the-Knee Lesions in PAD Patients

Johnson & Johnson MedTech has released the one-year results of its DISRUPT BTK II study, reaffirming the safety and durability of the Shockwave Peripheral Intravascular Lithotripsy (IVL) System for the treatment of calcified below-the-knee (BTK) lesions in patients with peripheral artery disease (PA

Clinical Trials | 04/11/2025 | By Dineshwori 268

GC Biopharma's Anthrax Vaccine Shows Safety and Immunogenicity in Phase 2 trial

GC Biopharma's Anthrax Vaccine Shows Safety and Immunogenicity in Phase 2 trial

The Phase 2 clinical trial demonstrated that the anthrax vaccine by GC Biopharma elicited antibodies that neutralised the anthrax toxin at a level exceeding the pre-defined protective threshold. This finding indicates robust immunogenicity and suggests that BARYTHRAX can provide clinically meaningful protection against anthrax infection.

Clinical Trials | 03/11/2025 | By Dineshwori 395

 
 

 

 

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