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Indian Scientists Redefine 50-Year-Old Biological Principle

Indian Scientists Redefine 50-Year-Old Biological Principle

For nearly 50 years, biology has related the story of how bacteria turn their genes on with the help of the so-called “σ (sigma) cycle” – factors that bind RNA polymerase to initiate transcription and then dissociate to allow elongation. This concept was built largely on observations of bacterial strain E. coli σ70.

Bose Institute | 03/03/2026 | By News Bureau 103


 

 

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