Insilico Medicine Advances AI-Discovered IPF Drug Rentosertib into Phase III Clinical Trial
Rentosertib, formerly known as ISM001-055/INS018_055, is a potentially first-in-class oral small-molecule inhibitor targeting TNIK (TRAF2 and NCK-interacting kinase) for the treatment of IPF, a progressive and irreversible lung disease with limited treatment options.
Insilico Medicine | 08/07/2026 | By Abha
Insilico Medicine and Takeda Collaborate on AI Drug Discovery
Takeda and Insilico Medicine are collaborating to advance Artificial Intelligence (AI)-powered drug discovery, leveraging the Pharma.AI platform to accelerate the development of therapeutics.
Insilico Medicine | 02/07/2026 | By News Bureau
Insilico Medicine and SK Biopharmaceuticals have entered an Artificial Intelligence (AI)-powered drug discovery collaboration worth up to USD 2.5 billion to develop innovative therapies for neuroimmune disorders.
Insilico Medicine | 23/06/2026 | By News Bureau | 409
Insilico Begins Phase 1 Trial of AI-Designed NLRP3 Inhibitor ISM8969
Insilico Medicine has completed first-in-human dosing of its AI-designed NLRP3 inhibitor ISM8969 in a phase 1 clinical trial. The oral, brain-penetrant therapy is being developed with Hygtia Therapeutics for chronic neuroinflammation and CNS disorders, including Parkinson’s disease, marking a key milestone in AI-driven drug development.
Insilico Medicine | 18/06/2026 | By News Bureau
Insilico Medicine and Ribo Partner on AI-Powered RNA Therapeutics Development
Insilico Medicine and Ribo partner to accelerate RNA interference and oligonucleotide drug development using Artificial Intelligence (AI)I-powered discovery platforms and automated laboratory technologies.
Insilico Medicine | 13/05/2026 | By News Bureau | 138
Eli Lilly Eyes USD 2 Billion AI Drug Discovery Deal with Insilico Medicine
Eli Lilly is set to enter into a deal worth over USD 2 billion with Hong Kong-based Insilico Medicine to accelerate drug discovery using artificial intelligence, signaling a major push toward AI-driven pharmaceutical innovation.
Insilico Medicine | 30/03/2026 | By Darshana | 185
Insilico Medicine Launches PandaClaw AI Platform for Drug Discovery
Insilico Medicine launches PandaClaw AI platform to accelerate drug discovery, enabling real-time analysis, target identification and disease hypothesis generation through an intuitive natural language interface.
Insilico Medicine | 24/03/2026 | By News Bureau | 146
TaiGen Biotechnology doses first participant in Phase I trial of ISM4808, an AI-designed oral therapy from Insilico Medicine for chronic kidney disease-related anemia.
Insilico Medicine | 09/03/2026 | By News Bureau | 226
Insilico Medicine Receives USD 5 Million from Menarini
Insilico received an additional $5 million milestone from Menarini following first-in-patient dosing in a Phase I trial of MEN2501, a generative AI-designed KIF18A inhibitor for chromosomally unstable solid tumours.
Insilico Medicine | 05/02/2026 | By News Bureau | 156
Insilico Medicine and Qilu Pharmaceutical Sign USD 120 Million Cardiometabolic Drug Deal
According to the agreement, Insilico Medicine will utilise its proprietary Pharma.AI platform to focus on the design and optimisation of novel small molecules for treating metabolic diseases, while Qilu Pharmaceutical Group will be responsible for subsequent development and commercialisation procedures.
Insilico Medicine | 28/01/2026 | By News Bureau | 155
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