In its virtual showroom, Pfeiffer Vacuum presents a variety of different leak testing methods for pharmaceutical packaging (container closure integrity testing or CCIT). Visitors to the site will find information about the challenges of leak testing IV bags, syringes, blister packs, plastic bottles, vials and other non-porous containers. At the virtual trade show booth, visitors will learn about Pfeiffer Vacuum’s unique portfolio of leak detectors. Informative videos explain the different technologies used – helium mass spectrometry, optical emission spectroscopy and mass extraction. 

A tight and reliable seal is essential in primary packaging for drugs. Contamination such as humidity, oxygen or microbiological ingress can considerably impact drug quality throughout the product life cycle. To prevent risks such as the stability failure of highly moisture-sensitive drugs (such as dry powder for inhalation) or biological ingress into parenteral drugs, integrity tests with a high sensitivity are required.

As well as presenting the different leak testing methods for pharmaceutical packaging, the showroom also provides more information on individual feasibility studies. The experts from Pfeiffer Vacuum use studies like these to visualize the particular packaging and test the possible use of CCIT. Pfeiffer Vacuum uses the three CCIT technologies to obtain a realizable detection limit and cycle time for the packaging.